Saturday, August 20, 2005
There have been a couple of articles relevant to prognostication in the last week. First, Annals of Internal Medicine has an article validating the International Prognostic Index (which uses age, disease stage, serum lactate dehydrogenase, ECOG performance status, and extent of extranodal disease to evaluate prognosis in AIDS related lymphoma) in the era of HAART & finds that it, along with the CD4 count, is valid. Those with the worst score had a 1 year survival of ~15%.
JAMA has an article looking at the epidemiology of acute renal failure in critically ill patients, finding that hospital mortality was 60%.