Saturday, March 11, 2006

Decision making; supportive care vs. nano-technology; the DEA FAQ; force-feeding prisoners; AAHPM PIT-SIG

I don't know if it's because I'm too busy, or because so much stuff is coming out, or because Christian is semi-out-of-commission with his fatherly duties, but I'm having a hard time keeping up with everything pouring out right now. Thus you are being treated to more digest like summaries of publications. I will get back to cranky reviews at some point hopefully soon.

So, in brief...
Journal of Clinical Oncology has an article on patients' decision making processes regarding chemotherapy for metastatic breast cancer. Among other things it looks at patients' perceptions of being active, passive, or collaborative decision makers, with some interesting findings (about half the cohort described themselves as passive decision makers--doing whatever the doctor recommends). However this is a relatively small single institution study & I'm not sure if much can be made of their findings. Studies like these are interesting snap shots into some of the contingencies of difficult medical decision making, but I'm generally not sure what can be done with their findings other than than communication and decision making support should be honest, empathetic, individualized, etc.

The March 10th JCO is all about neuro-oncology and has a couple of articles to note, especially us non-oncologists who help care for these patients at the end of life--good background information, etc. One is a review of current treatment of high-grade astrocytomas (which, as far as I can tell, means glioblastomas). It is a nice overview of the field. Continuing my score-card of noting how much of a nod palliative/supportive care gets in oncology review articles of highly-lethal cancers, this piece gives pall/supp care a small paragraph (approximately the same amount of column space as nano-particle technology). Perhaps this should become my new standard of 'equal coverage'--supportive care vs nanotechnology. There's also a nice, general review of whole brain radiotherapy for brain mets.

Also the law...
The current Pain Medicine has a special section on the DEA and pain medicine, focusing mostly on the infamous DEA FAQ (Table of Contents here--the articles are 2/3 of the way down under "Forensic Pain Medicine Section"). The section has multiple commentaries by pain docs (including Steve Passik) about this; a lot of them focusing on the controversies and confusions surrounding "Do not fill" prescriptions (for example--writing a prescription dated March 10, 2006 but noting on it "Do not fill until April 10, 2006"). Of particular interest in a brief legal history of the DEA surrounding DNFs by a lawyer. The general consensus seems to be that the DEA is not genuinely interested in an honest dialogue with docs or patients about this, and that the DEA is perpetuating a climate where docs are hesitant to treat pain with controlled substances. Perhaps things will get better in 2009 (ahem)....

While we're there there's also a case report about botox for post-herpetic neuralgia.

NEJM continues the DEA trend with a legal exegesis of the Supreme's Court's physician assisted suicide/Controlled Substances Act decision by GJ Annas (free full text is available).

As well as ethics...
Lancet has published a letter about the practice of force-feeding inmates at Guantanamo Bay (and yes, I know I vowed never to directly link to the Lancet website again because of their policy of forced sign-ins, but this is not listed in PubMed yet and I'm not organized well enough to keep track of this until it is).

Oh yes and the PIT-SIG...
By the way if you're a palliative care professional in training (medical students, residents, fellows, as well as allied professionals) the AAHPM's Professionals In Training Special Interest Group has a blog (pitsig.blogspot.com) about the group's activities. The PIT-SIG also has an email listserv, and we are generally very interested in hearing from PITs about what's going on, how the PIT-SIG can help people, whatever. Drop Christian or me a note if you're interested.

5 Responses to “Decision making; supportive care vs. nano-technology; the DEA FAQ; force-feeding prisoners; AAHPM PIT-SIG”

Anonymous said...
March 11, 2006

I like your score card idea. It is simliar to the percent of text given to prognosis as compared to diagnosis or treatment in medical textbooks over the years. Needless to say the percent dedicated to prognosis is even less and elss as diagnostic and therapeutics advance. I will try and get the citation for this reasearch from Christakis' book Death Foretold.

As far as my fatherly duties, the twins are still in the NICU feeding and growingf and learning how to eat on their own. It has given me a new level of respect for feeds by NG tube. So a question that struck as I held my son while he was getting EBM (not evidenced based medicine, but expressed breast milk) by NG tube was: Is expressed breast milk (a natural product) given by NG Tube (medical technology) artificial in the sense of artificial nutrition?

Something only a palliative care doc might think of....

And please check out the PIT-SIG blog too..

-Christian Sinclair, MD (at work and could not get my log in to go through...)


Anonymous said...
March 11, 2006

And as far as high-grade astrocytomas, my understanding is that they include WHO Grade 3 (Anaplastic astrocytoma) and Grade 4 (glioblastoma multiforme-GBM), wheras low-grade astrocytomas are Grade 1 (pliocystic astrocytoma) and Grade 2 (diffuse astrocytoma).

I ahve not pulled the article itslef to see how their definitions fit.

-Christian Sinclair, MD (again from work)


Drew Rosielle, MD said...
March 11, 2006

Thanks for the clarification of high grade astrocytomas.

It is "artificial" in my opinion--my operating definition, which makes sense based on the literature, is anything other than the swallowed, oral route.

If I ever get the time it actually would be a fun project to keep an official score card on review articles. Going with the nanotechnology thing maybe the standard could be whether the review article devotes more space to supportive care vs. the most experimental, years-away, not-evidence-based, and/or generally unproven treatment mentioned in the article.

--Drew (working, but not at work).


Alex DeLuca, M.D., MPH said...
April 23, 2006

Thank you for your efforts - I especially appreciate your review of the DEA FAQ Debacle, and of the special issue of Pain Medicine (Jan '06) devoted to it.

I would like your readers to know that I have made several of those article available in full, and have provided links to background articles on the subissues raised; for example, prescription monitoring programs like NASPER, ethical/moral aspects of pain management, and the Dr. William Hurwitz situation.

The collection is entitled: "THE PATHOLOGICAL DEA - The War on Doctors and the Pain Crisis in the Aftermath of the DEA FAQ Debacle" at:
http://www.doctordeluca.com/Library/WOD/PathologicalDea06.htm

Your readers might also be interested in:
"War on Doctors and Pain Crisis Weekly" RSS feed:
http://www.doctordeluca.com/wod-main.xml

and,

"Harm Reduction for Alcohol Disorders Weekly" RSS feed:
http://www.doctordeluca.com/abshr-main.xml

Thanks again Drs. Rosielle and Sinclair so much for following these important issues.

Sincerely,

..alex...

Alexander DeLuca, M.D., MPH
doctordeluca@gmail.com
http://www.doctordeluca.com/


Drew Rosielle, MD said...
April 23, 2006

Thanks Alex for the comment and links. I've been perusing your website and would recommend it to our readers who are interested in the topic.

Best

Drew